Is it possible to run Multiple copies of PHPNuke (seperate directories, and domain names) using 1 Database? I know the Default prefix for tables in the database is Nuke_ , and you can change the prefix in the config, but is it possible to run a second copy using a different prefix within the same database?

Well yes its possible, just change the prefix, you could also use the same prefix for users if you wanted both sites to have the same memberships.

Iam assuming your Domains are hosted in the same hosting panel ?

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